metaPreg - Miconazole (local route only) during pregnancy

Miconazole (local route only) updated on 01-29-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.27 [1.03, 1.58]	0%	2 studies	28,648	668	not evaluable	ROB	1.86 [1.20; .]
Cleft lip with or without cleft palate	2.43 [0.91, 6.47]	40%	2 studies	1,502	530	not evaluable	ROB	-
Congenital heart defects	1.11 [0.73, 1.69]	0%	2 studies	6,886	543	not evaluable	ROB	-
Major congenital malformations	1.27 [1.03, 1.58]	0%	2 studies	28,648	668	not evaluable	ROB	1.86 [1.20; .]
Limb defects	2.10 [1.12, 3.94]	-	1 study	1,437	313	not evaluable	ROB	3.62 [1.48; .]
Polydactyly	6.00 [2.38, 15.10]	-	1 study	1,744	224	not evaluable	ROB	11.48 [4.20; .]
12 non statistically significant endpoints reported in only one study
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
1 non statistically significant endpoints reported in only one study