Etizolam

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Noh, 2022	South Korea 2011 - 2018	All pregnancies in women aged 20 to 45 years at delivery resulting in live births from 1 January 2011 to 31 December 2018, in South Korea.	Pregnant women who filled at least Etizolam prescription during the first trimester (first 90 days of pregnancy).	unexposed, sick Pregnant women who were not prescribed any benzodiazepine from 3 months before the last menstrual period to the end of the first trimester (with similar psychiatric conditions after propensity score).	3665 / 3053381	Propensity scored adjusted for indications and led to an unexposed cohort with similar psychiatric conditions => considered as unexposed, sick control groups.
Yamane, 2011	Japan Not specified.	Pregnant women who visited the Counseling Clinic for Pregnancy and Medicine of Toranomon Hospital.	Pregnant women who used Etizolam in the early stage of pregnancy.	unexposed (general population or NOS) Pregnant women who used acetaminophen without teratogenic effects.	224 / -9	Number of pregnant women in the control group not provided in the Abstract.

Study	Country Study period	Case	Control	Sample size	Rmk