Oxazepam (Psy and mixed indications)

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Källén, 2013	Swedish 1996 - 2011	Nearly all births in Sweden during the study period (1,575,847) are registered in The Swedish Medical Birth Register.	Infants whose mothers used oxazepam in early pregnancy. (This is a subgroup of exposure among the whole exposed group considered in the study).	unexposed (general population or NOS) Infants in population whose mothers used at least one of a central nervous system active drugs (less than 3%) or weren't exposed in early pregnancy.	843 / 1575847	Follow-up period known thanks to author's email reply.

Study	Country Study period	Case	Control	Sample size	Rmk
Bonnot, 2001	France 1976 - 1998	Infants with the studied congenital malformation.	Infants with a malformations other than this one studied.	-9 / -9	Data completed with Bonnot 2003. Total number of infants with a congenital malformation is 13703, but the number of cases changes according to the studied malformations. Raw data not sufficient to calculate OR (data for 'control' groups not available).
Cornel - The NNL registry, 1996	The Netherlands 1981 - 1994	Infants with a cleft lip with or without cleft palate.	All infants notified with other anomalies.	277 / 3737
Sheehy, 2019	Canada 1998 - 2015	Pregnancies ending with spontaneous abortion (pregnancy loss between between the beginning of the sixth week of gestation and the 19th completed week of gestation, excluding planned or induced abortions).	Pregnancies ending with live births (5 for each case) randomly selected at the index date and matched with the case pregnancy by gestational age and calendar year.	27149 / 134305