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Greenberg, 1977
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case control
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Medical officers or community physicians were asked to identify the baby and the general practitioner, who was then interviewed by one of the Committee's medical field workers notably about drugs prescribed during the first trimester (only information obtained from written notes was used).
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The doctor, midwife, or health visitor attending the birth of an abnormal baby may report the abnormality to the area health authority. This information is then passed to the OPCS. Though voluntary, it is believed that notification of visible and severe malformations is reasonably complete.
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It was accepted as controls only babies born within three months of the case baby. Maternal age and parity similar in cases and controls.
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Yaris, 2005
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prospective cohort
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Data surveyed by the interviews.
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Examinations were made by obstetric ultrasound for the mothers and birth weight and height, gestational age, APGAR scores, congenital malformation and developmental problems for the babies. Periodic checks of all the babies in the neonatal period, were made the first year, and following years.
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None for this group of exposure.
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