Pantoprazole

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
All congenital malformations (majors, minors, majors and minors, or unspecified)1.28 [0.83, 1.99]0%2 studies21,919591not evaluable ROB-
Major congenital malformations1.28 [0.83, 1.99]0%2 studies21,919591not evaluable ROB-

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Low birth weight (< 2500g)1.05 [0.95, 1.16]-1 study104,4546,180not evaluable ROB-
Preterm (< 37 weeks)1.30 [0.57, 2.99]-1 study9348not evaluable ROB-

Intrauterine deaths
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Early intrauterine death (< 22 weeks)0.27 [0.04, 1.98]-1 study5953not evaluable ROB-
Ectopic pregnancy--0 study-
Elective/induced termination of pregnancy1.87 [0.55, 6.37]-1 study3053not evaluable ROB-
Late intrauterine deaths (> 22 weeks)8.33 [0.74, 93.34]-1 study353not evaluable ROB-

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