metaPreg - Miconazole (all routes except local only) during pregnancy

Miconazole (all routes except local only) updated on 01-29-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.02 [0.88, 1.18]	-	1 study	6,564	2,236	not evaluable	ROB	-
Ano-rectal atresia and stenosis	1.77 [0.54, 5.77]	-	1 study	209	42	not evaluable	ROB	-
Cleft lip with or without cleft palate	1.01 [0.49, 2.10]	-	1 study	1,086	48	not evaluable	ROB	-
Congenital heart defects	0.52 [0.28, 0.98]	-	1 study	3,049	52	not evaluable	ROB	3.26 [.; 1.19]
Craniosynostosis	0.55 [0.13, 2.27]	-	1 study	447	41	not evaluable	ROB	-
Diaphragmatic hernia	0.89 [0.21, 3.70]	-	1 study	275	41	not evaluable	ROB	-
Gastroschisis	0.27 [0.04, 1.95]	-	1 study	455	40	not evaluable	ROB	-
Hypospadias	0.47 [0.15, 1.53]	-	1 study	776	42	not evaluable	ROB	-
Microcephaly / Small head circumference for gestational age	0.96 [0.06, 16.12]	-	1 study	57	216	not evaluable	ROB	-
Neural Tube Defects	1.64 [0.82, 3.30]	-	1 study	750	49	not evaluable	ROB	-
Long term consequences
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Leukemia	0.94 [0.53, 1.66]	-	1 study	243	61	not evaluable	ROB	-
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