metaPreg - Clobazam (Psy and Mixed indications) during pregnancy

Clobazam (Psy and Mixed indications) updated on 02-10-2025

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
Microcephaly / Small head circumference for gestational age	0.98 [0.06, 16.34]	-	1 study	133,324	17	not evaluable	ROB	-
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.18 [0.73, 1.91]	-	1 study	156,913	218	not evaluable	ROB	-
Congenital heart defects	1.28 [0.69, 2.39]	-	1 study	83,595	218	not evaluable	ROB	-
Major congenital malformations	1.18 [0.73, 1.91]	-	1 study	156,913	218	not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Small for gestational age (weight)	1.70 [0.77, 3.75]	-	1 study	65,123	30	not evaluable	ROB	-
Preterm (< 37 weeks)	3.30 [2.05, 5.32]	-	1 study	33,979	30	not evaluable	ROB	6.05 [3.51; .]
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