id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S2757 R3945 |
Zambelli-Weiner (Unexposed control, NOS), 2019 | Atrial septal defect | 1st trimester | nested case control | unexposed (general population or NOS) | Adjustment: Yes | 1.49 [1.32;1.69] | 15/893 813/113,919 | 828 | 893 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S2853 R3967 |
Parker, BDS study, 2018 | Atrial septal defect | 1st trimester | case control | unexposed, sick | Adjustment: Yes | 0.80 [0.50;1.20] | 24/399 340/5,838 | 364 | 399 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S2756 R3683 |
Parker, NBDPS study, 2018 | Atrial septal defect | 1st trimester | case control | unexposed, sick | Adjustment: Yes | 0.90 [0.60;1.30] | 41/294 1,164/7,662 | 1,205 | 294 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 3 studies | 1.06 [0.68;1.65] | 2,397 | 1,586 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Unexposed control, NOS;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded