id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S13666 R53067 |
Reynolds, 2022 | Low birth weight (<2.5 kg) | throughout pregnancy | retrospective cohort | unexposed, sick | Adjustment: No Indication HCQ: Systemic lupus erythematosus (SLE) | 1.24 [0.58;2.66] | 39/146 31/130 | 70 | 146 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S13670 R53108 |
Tang, 2022 | Low birth weight (< 2500 g) | during pregnancy (anytime or not specified) | retrospective cohort | unexposed, sick | Adjustment: No Indication HCQ: IgA nephropathy | 1.84 [0.62;5.46] C | 7/25 11/63 | 18 | 25 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S13697 R53285 |
Louthrenoo, 2021 | Low birth weight | during pregnancy (anytime or not specified) | retrospective cohort | unexposed, sick | Adjustment: No Indication HCQ: Systemic lupus erythematosus (SLE) | 0.60 [0.21;1.70] | 16/35 21/36 | 37 | 35 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S13687 R53202 |
Leroux, 2015 | Intrauterine growth restriction (body weight < 10th percentile) at birth | throughout pregnancy | retrospective cohort | unexposed, sick | Adjustment: No Indication HCQ: Systemic lupus erythematosus (SLE) | 0.29 [0.09;0.93] C | 4/38 22/77 | 26 | 38 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 4 studies | 0.83 [0.40;1.74] | 151 | 244 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
Asymetry test p-value = NaN (by Egger's regression)
not enought points
excluded