Methotrexate (Pre-conception only)

Study Reference
Dawson, 2014

Dawson Maternal exposure to methotrexate and birth defects: a population-based study. Am J Med Genet A 2014; 164A:2212-6

Howren, 2020

Howren Perinatal exposure to conventional synthetic disease-modifying anti-rheumatic drugs in women with rheumatic disease and neonatal outcomes: a population-based study. Clin Exp Rheumatol ; 38:1080-1087

Matsui, 2003

Matsui Risk of abnormal pregnancy completing chemotherapy for gestational trophoblastic tumor. Gynecol Oncol 2003; 88:104-7

Svirsky, 2017

Svirsky Outcomes of conception subsequent to methotrexate treatment for an unruptured ectopic pregnancy. Int J Gynaecol Obstet 2017; 139:170-173

Svirsky The safety of conception occurring shortly after methotrexate treatment of an ectopic pregnancy. Reprod Toxicol 2009; 27:85-7

Svirsky, 2009

Svirsky The safety of conception occurring shortly after methotrexate treatment of an ectopic pregnancy. Reprod Toxicol 2009; 27:85-7

Weber-Schoendorfer (Controls exposed to other treatment, sick), 2014

Weber-Schoendorfer Pregnancy outcome after methotrexate treatment for rheumatic disease prior to or during early pregnancy: a prospective multicenter cohort study. Arthritis Rheumatol 2014; 66:1101-10

Weber-Schoendorfer (Controls unexposed, disease free), 2014

Weber-Schoendorfer Pregnancy outcome after methotrexate treatment for rheumatic disease prior to or during early pregnancy: a prospective multicenter cohort study. Arthritis Rheumatol 2014; 66:1101-10