Mirtazapine

Study Reference
Anderson, 2020

Anderson Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects. JAMA Psychiatry 2020; 77(12):1246-1255.

Nembhard Maternal and infant genetic variants, maternal periconceptional use of selective serotonin reuptake inhibitors, and risk of congenital heart defects in offspring: population based study. BMJ 2017; 356:j832

Chan (Controls exposed to SSRIs), 2024

Chan Prenatal antidepressant use and risk of congenital malformations: A population-based cohort study. Psychiatry Res 2024; 339:116038

Chan (Controls unexposed, pop general), 2024

Chan Prenatal antidepressant use and risk of congenital malformations: A population-based cohort study. Psychiatry Res 2024; 339:116038

Djulus (Controls exposed to other antidepressants), 2006

Djulus Exposure to mirtazapine during pregnancy: a prospective, comparative study of birth outcomes. J Clin Psychiatry 2006; 67:1280-4

Djulus (Controls unexposed, disease free), 2006

Djulus Exposure to mirtazapine during pregnancy: a prospective, comparative study of birth outcomes. J Clin Psychiatry 2006; 67:1280-4

Einarson, 2009

Einarson A Incidence of major malformations in infants following antidepressant exposure in pregnancy: results of a large prospective cohort study. Can J Psychiatry 2009;54:242-6

Gungor (Controls exposed to SSRI), 2019

Gungor, B.B. Comparison of the groups treated with mirtazapine and selective serotonine reuptake inhibitors with respect to birth outcomes and severity of psychiatric disorder Psychiatry and Clinical Psychopharmacology 2019; 29:822-.

Gungor (Controls unexposed, disease free), 2019

Gungor, B.B. Comparison of the groups treated with mirtazapine and selective serotonine reuptake inhibitors with respect to birth outcomes and severity of psychiatric disorder Psychiatry and Clinical Psychopharmacology 2019; 29:822-.

Gungor (Controls unexposed, sick), 2019

Gungor, B.B. Comparison of the groups treated with mirtazapine and selective serotonine reuptake inhibitors with respect to birth outcomes and severity of psychiatric disorder Psychiatry and Clinical Psychopharmacology 2019; 29:822-.

Heuvelman, 2023

Heuvelman Antidepressants in pregnancy: applying causal epidemiological methods to understand service-use outcomes in women and long-term neurodevelopmental outcomes in exposed children. Health Technol Assess 2023; 27:1-83

Källen, 2013

Källen B The use of central nervous system active drugs during pregnancy. Pharmaceuticals (Basel) 2013;6:1221-86

Kieler, 2015

Kieler Use of antidepressants and association with elective termination of pregnancy: population based case-control study. BJOG 2015; 122:1618-24

Kolding (Controls unexposed, disease free), 2021

Kolding Antidepressant use in pregnancy and severe cardiac malformations: Danish register-based study. BJOG 2021; 128:1949-1957

Kolding (Controls unexposed, sick), 2021

Kolding Antidepressant use in pregnancy and severe cardiac malformations: Danish register-based study. BJOG 2021; 128:1949-1957

Laspro, 2024

Laspro Association of Commonly Prescribed Antepartum Medications and Incidence of Orofacial Clefting. Cleft Palate Craniofac J 2024; :10556656241237679

Lee (Controls exposed to SSRI), 2025

Lee Antidepressant use during pregnancy and risk of obstetrics and neonatal outcomes: A propensity score-weighted population-based cohort study in 2003-2018. Eur Neuropsychopharmacol 2025; 96:36-45

Lee (Controls unexposed, general pop), 2025

Lee Antidepressant use during pregnancy and risk of obstetrics and neonatal outcomes: A propensity score-weighted population-based cohort study in 2003-2018. Eur Neuropsychopharmacol 2025; 96:36-45

Martin, 2024

Martin Antidepressant use during pregnancy and birth outcomes: analysis of electronic health data from the UK, Norway, and Sweden. medRxiv 2024; :

Ostenfeld, 2022

Ostenfeld Mirtazapine exposure in pregnancy and fetal safety: A nationwide cohort study. Acta Psychiatr Scand 2022; 145:557-567

Ozturk, 2016

Ozturk, Z. Safety of psychotropic medications in pregnancy: An observational cohort study Klinik Psikofarmakoloji Bulteni 2016; 26:229-.

Palmsten a (control exposed to SSRIs), 2013

Palmsten Antidepressant use and risk for preeclampsia. Epidemiology 2013; 24:682-91

Palmsten a (Controls unexposed, sick), 2013

Palmsten Antidepressant use and risk for preeclampsia. Epidemiology 2013; 24:682-91

Palmsten b, 2013

Palmsten Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States. BMJ 2013; 347:f4877

Winterfeld (Controls exposed to SSRI), 2015

Winterfeld Pregnancy outcome following maternal exposure to mirtazapine: a multicenter, prospective study. J Clin Psychopharmacol 2015; 35:250-9

Winterfeld (Controls unexposed, NOS), 2015

Winterfeld Pregnancy outcome following maternal exposure to mirtazapine: a multicenter, prospective study. J Clin Psychopharmacol 2015; 35:250-9

Yaris, 2005

Yaris Psychotropic drugs in pregnancy: a case-control study. Prog. Neuropsychopharmacol. Biol. Psychiatry 2005; 29:333-8