Bendroflumethiazide (versus unexposed)

Study	Country Study period	Population source	Exposure definition	Non-exposure definition	Sample size	Rmk
Leather, 1968	United Kingdom Not specified.	Patients that were referred from the antenatal clinics and from obstetric wards, diagnosed with early (before 20 weeks of gestation) or late (normontensive before 20 weeks) hypertension.	Pregnant patients with early hypertension (before 20 gestational weeks) randomly allocated to treatment group, i.e bendrofluazide 5-10 mg daily with potassium supplements and methyldopa 0-5-2g daily in divided doses.	unexposed, sick Pregnant patients with early hypertension (before 20 gestational weeks) randomly allocated to control group.	23 / 24	Data related to chronic hypertension were reported here.

Study	Country Study period	Case	Control	Sample size	Rmk