Study Type of data Exposure measurement Outcome assessment Adjustment
Fejzo, 2015 case control Participants were asked to submit their medical records and complete an online survey regarding treatment. Participants were asked to submit their medical records and complete an online survey regarding outcomes. A follow-up survey was administered on the diagnosis of childhood emotional, behavioral, and learning disorders. Cases and controls were well-matched for mean maternal age, spontaneous labor, delivery method, and use of assisted reproduction. Children of cases and controls were well-matched for gender and age, with the average age between 8 and 9 years old.
Fejzo, 2013 case control Participants were asked to submit their medical records and complete an online surveyregarding treatment. The majority of participants, both cases and controls, joined the study and began the survey during their pregnancies. Participants were asked to submit their medical records and complete an online surveyregarding outcomes. The majority of participants, both cases and controls, were automatically prompted to complete the survey on outcome following their due date. None.
Shapira, 2020 retrospective cohort Medical records. Prenatal surveillance findings and pregnancy outcomes were extracted from medical records. All patients treated with granisetron were contacted by phone and were asked to participate in the study by answering a detailed questionnaire, notably on current infant health, and congenital anomalies. Granisetron exposed patients were matched with controls by age (±2 years) and gestational age at ER visit (±2 weeks).

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