Desvenlafaxine

Study Type of data Exposure measurement Outcome assessment Adjustment
Anderson, 2020 case control Information on exposure to SSRIs and other potential risk factors during pregnancy were collected by standardized telephone interviews with mothers of case and control infants, conducted 6 weeks to 24 months after the EDD. Case infants were ascertained through population-based birth-defects surveillance systems in 10 U.S. states. Controls were selected randomly from the same geographic areas. Clinical data were abstracted from medical records and classified by clinician geneticists and other clinicians. Adjusted for maternal race/ ethnicity, prepregnancy body mass index, education, and early pregnancy smoking and alcohol use
Marks, 2021 retrospective cohort Data were obtained from electronic medical records (EMRs) through the Regenstrief Institute in Indianapolis. Diagnoses were extracted from the electronic database discharge summaries, delivery records, and/or International Classification of Diseases (ICD) codes. Clinical diagnosis were extracted from the delivery discharge summary written by the clinician caring for the infant. All results reported as aOR (95% CI) controlling for maternal race, age, insurance, and gestational age at delivery.

master protocol