Interferon beta 1b (IFN-β1b)

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROB
All congenital malformations (majors, minors, majors and minors, or unspecified)no data1.71 [0.37, 7.96]0%2 studies5,00121not evaluable NApptx
Major congenital malformationsno data1.88 [0.33, 10.69]0%2 studies4,99821not evaluable NApptx

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROB
Preterm (< 37 weeks)no data1.32 [0.31, 5.56]61%3 studies20668not evaluable NApptx

Maternal consequences
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROB
Preeclampsiano data--0 studypptx
1 non statistically significant endpoints reported in only one study

Neonatal disorders
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROB
2 non statistically significant endpoints reported in only one study

Long term consequences
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROB
1 non statistically significant endpoints reported in only one study

Intrauterine deaths
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROB
Intrauterine deaths (as a whole)no data1.70 [0.43, 6.67]57%2 studies6470not evaluable NApptx
1 non statistically significant endpoints reported in only one study