metaPreg - Zonisamide (Epilepsy) during pregnancy

Zonisamide (Epilepsy)

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)	1.01 [0.19, 5.31]	0%	3 studies	81	112	not evaluable	ROB	-
Major congenital malformations	1.01 [0.19, 5.31]	0%	3 studies	81	112	not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Low birth weight (< 2500g)	2.17 [0.91, 5.14]	-	1 study	26	98	not evaluable	ROB	-
Preterm (< 37 weeks)	1.81 [0.85, 3.87]	-	1 study	37	98	not evaluable	ROB	-
Small for gestational age (weight)	1.90 [1.20, 3.00]	-	1 study		125	not evaluable	ROB	3.21 [1.69; .]
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Intrauterine deaths (as a whole or unspecified)	1.16 [0.02, 62.85]	-	1 study		13	not evaluable	ROB	-
Neuro-developmental disorders
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Language disorders/delay	0.33 [0.10, 1.06]	-	1 study		11	not evaluable	ROB	-
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