Rabeprazole

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
All congenital malformations (majors, minors, majors and minors, or unspecified)1.11 [0.72, 1.73]21%2 studies108,27513,456not evaluable ROB-
Major congenital malformations1.11 [0.72, 1.73]21%2 studies108,27513,456not evaluable ROB-
Cleft palate1.22 [0.72, 2.07]-1 study2,29613,414not evaluable ROB-
Congenital heart defects1.05 [0.93, 1.19]-1 study42,41913,414not evaluable ROB-
Hydrocephaly1.57 [0.75, 3.30]-1 study79113,414not evaluable ROB-
Hypospadias0.83 [0.42, 1.63]-1 study1,8086,899not evaluable ROB-

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Low birth weight (< 2500g)1.00 [0.92, 1.08]-1 study104,73211,934not evaluable ROB-

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