metaPreg - Fingolimod during pregnancy

Fingolimod updated on 06-01-2019

Table Graphic exposition period:

Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Congenital malformations
Major congenital malformations	0.85 [0.06, 12.12]	30%	2 studies	6	74	not evaluable	ROB	-
All congenital malformations (majors, minors, majors and minors, or unspecified)	0.12 [0.00, 7.22]	-	1 study	3	32	not evaluable	ROB	-
Growth parameters and prematurity
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Preterm (< 37 weeks)	1.32 [0.47, 3.69]	0%	2 studies	192	50	not evaluable	ROB	-
Intrauterine deaths
Adverse outcome	OR 95%CI	I2	k	No. cases	No. exposed	publication bias	ROB	E-value
Elective/induced termination of pregnancy	0.88 [0.16, 4.97]	75%	3 studies	82	136	not evaluable	ROB	-
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions	0.77 [0.30, 2.00]	0%	2 studies	28	124	not evaluable	ROB	-
Intrauterine deaths (as a whole or unspecified)	1.30 [0.16, 10.24]	-	1 study	51	12	not evaluable	ROB	-
Therapeutic terminations of pregnancy	0.98 [0.06, 16.09]	-	1 study	2	63	not evaluable	ROB	-
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