Propranolol (versus unexposed)

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations Hypospadias Van Zutphen, 2014 Bergman, 2018 21.60[0.24; 10.83]10,2847not evaluable All congenital malformations (majors, minors, majors and minors, or unspecified) Delteil, 2024 10.75[0.37; 1.53]4,062442not evaluable Atrial septal defect Bergman, 2018 10.60[0.13; 2.88]7,01231not evaluable Cleft lip with or without cleft palate Bergman, 2018 11.40[0.40; 4.90]3,62432not evaluable Cleft palate Bergman, 2018 12.60[0.78; 8.67]2,00132not evaluable Club foot / Talipes equinovarus Bergman, 2018 11.80[0.62; 5.25]4,413-not evaluable Congenital heart defects Bergman, 2018 10.70[0.34; 1.46]32,44441not evaluable Major congenital malformations Delteil, 2024 10.75[0.37; 1.53]4,062442not evaluable Neural Tube Defects Bergman, 2018 1----- Growth parameters and prematurity Small for gestational age (weight) Lieberman, 1978 Tanaka, 2016 Duan, 2018 Delteil, 2024 42.63[1.25; 5.52]46,396801not evaluable Low birth weight (< 2500g) Ishibashi, 2017 Duan, 2018 21.53[1.11; 2.11]19,451515not evaluable Very low birth weight (< 1500g) Duan, 2018 11.79[0.89; 3.61]3,449489not evaluable Maternal consequences Assisted deliveries (forceps, vacuum, ...) Duan, 2018 10.74[0.37; 1.49]8,241489not evaluable Caesarean Duan, 2018 11.30[1.07; 1.56]104,366489not evaluable Preeclampsia Duan, 2018 10.99[0.32; 3.07]2,333489not evaluable Neonatal disorders Low Apgar score (< 7) (at 1 min) Duan, 2018 11.60[1.13; 2.26]16,789489not evaluable Low Apgar score (< 7) (at 10 min) Duan, 2018 13.24[1.45; 7.26]1,436489not evaluable Low Apgar score (< 7) (at 5 min) Duan, 2018 11.78[0.84; 3.76]3,031489not evaluable Neonatal death (< 28 days of life) Lieberman, 1978 10.29[0.01; 6.93]29not evaluable Intrauterine deaths Late intrauterine deaths (> 22 weeks) Lieberman, 1978 114.00[1.86; 105.27]109not evaluable Perinatal death Lieberman, 1978 17.00[1.04; 46.95]129not evaluable0.0100.01.0

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