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Felbamate (Epilepsy = ALL indications)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Tomson (Felbamate), 2018
1
6.55
[
0.31
; 137.62]
74
3
not evaluable
Major congenital malformations
Tomson (Felbamate), 2018
1
6.55
[
0.31
; 137.62]
74
3
not evaluable
Neuro-developmental disorders
Neuro-developmental disorders (as a whole)
Katz (Felbamate), 2001
1
0.56
[
0.01
; 37.57]
-
5
not evaluable
0.0
100.0
1.0