meta
|
Preg
- medecines during pregnancy KB
Search
Ketoconazole (all routes except local only)
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Kazy, 2005 Molgaard-Nielsen, 2013
2
1.25
[
0.49
; 3.18]
48,004
83
not evaluable
Congenital heart defects
Kazy, 2005 Carter, 2008
2
3.11
[
0.81
; 11.97]
7,528
11
not evaluable
Major congenital malformations
Kazy, 2005 Molgaard-Nielsen, 2013
2
1.25
[
0.49
; 3.18]
48,004
83
not evaluable
Ano-rectal atresia and stenosis
Carter, 2008
1
22.78
[
0.45
; 1150.95]
209
1
not evaluable
Cleft lip with or without cleft palate
Carter, 2008
1
4.39
[
0.09
; 221.51]
1,086
1
not evaluable
Craniosynostosis
Carter, 2008
1
10.66
[
0.21
; 538.15]
447
1
not evaluable
Diaphragmatic hernia
Carter, 2008
1
17.32
[
0.34
; 874.73]
275
1
not evaluable
Gastroschisis
Carter, 2008
1
10.48
[
0.21
; 528.69]
455
1
not evaluable
Hypospadias
Carter, 2008
1
6.16
[
0.38
; 98.57]
776
2
not evaluable
Neural Tube Defects
Carter, 2008
1
6.37
[
0.40
; 101.99]
750
2
not evaluable
0.0
100.0
1.0
