Caftor

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations Major congenital malformations Chouchana (Controls unexposed, sick), 2025 10.72[0.27; 1.93]26148not evaluable Growth parameters and prematurity Preterm (< 37 weeks) Chouchana (Controls unexposed, sick), 2025 Jain, 2025 Salvatore, 2026 31.03[0.74; 1.43]220273not evaluable Extremely preterm (< 28 weeks) Chouchana (Controls unexposed, sick), 2025 10.33[0.02; 6.19]4147not evaluable Large for gestational age (weight) Chouchana (Controls unexposed, sick), 2025 11.22[0.66; 2.26]56147not evaluable Small for gestational age (weight) Chouchana (Controls unexposed, sick), 2025 10.38[0.19; 0.76]81147not evaluable Very preterm (28 to 32 weeks) Chouchana (Controls unexposed, sick), 2025 12.28[0.50; 10.29]7147not evaluable Low birth weight (< 2500g) Jain, 2025 10.90[0.43; 1.89]3967not evaluable Maternal consequences Caesarean Jain, 2025 Salvatore, 2026 20.89[0.55; 1.45]149103not evaluable Assisted deliveries (forceps, vacuum, ...) 0----- Gestational diabetes Chouchana (Controls unexposed, sick), 2025 12.84[1.87; 4.32]127148not evaluable Preeclampsia Chouchana (Controls unexposed, sick), 2025 11.19[0.49; 2.92]25148not evaluable Neonatal disorders Neonatal medical care Jain, 2025 11.29[0.68; 2.43]5675not evaluable Low Apgar score (< 7) (at 1 min) Jain, 2025 10.70[0.30; 1.65]2870not evaluable Low Apgar score (< 7) (at 5 min) Jain, 2025 10.76[0.18; 3.16]971not evaluable Intrauterine deaths Late intrauterine deaths (> 22 weeks) / Stillbirths Chouchana (Controls unexposed, sick), 2025 10.61[0.03; 12.74]2148not evaluable Therapeutic terminations of pregnancy Chouchana (Controls unexposed, sick), 2025 10.38[0.05; 3.04]9148not evaluable Early intrauterine deaths (< 22 weeks) / Spontaneous abortions Jain, 2025 10.71[0.33; 1.51]37101not evaluable0.020.01.0

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