Bupropion (Smoking cessation indication)

Table   Graphic  
individual studies
OutcomeTE95% CIn casesn exposedkPub. bias Congenital malformations Abdominal wall defects Tran, 2025 11.24[0.16; 9.59]-749not evaluable All congenital malformations (majors, minors, majors and minors, or unspecified) Tran, 2025 10.93[0.67; 1.29]4371,042not evaluable Annular pancreas Tran, 2025 19.90[0.20; 499.28]-749not evaluable Aortic valve atresia/stenosis Tran, 2025 19.90[0.20; 499.28]-749not evaluable Arhinencephaly/holoprosencephaly Tran, 2025 19.90[0.20; 499.28]-749not evaluable Atrial septal defect Tran, 2025 10.43[0.11; 1.65]40749not evaluable Atrioventricular septal defect Tran, 2025 11.10[0.06; 20.44]4749not evaluable Bilateral renal agenesis including Potter syndrome Tran, 2025 19.90[0.20; 499.28]-749not evaluable Bladder exstrophy and/or epispadia Tran, 2025 19.90[0.20; 499.28]-749not evaluable Cleft lip with or without cleft palate Tran, 2025 11.10[0.06; 20.44]4749not evaluable Cleft palate Tran, 2025 10.52[0.03; 8.95]9749not evaluable Club foot / Talipes equinovarus Tran, 2025 10.49[0.06; 3.83]11749not evaluable Coarctation of aorta Tran, 2025 10.90[0.05; 16.28]5749not evaluable Common arterial truncus Tran, 2025 19.90[0.20; 499.28]-749not evaluable Congenital heart defects Tran, 2025 10.55[0.21; 1.43]91749not evaluable Congenital hydronephrosis Tran, 2025 10.47[0.03; 8.04]10749not evaluable Diaphragmatic hernia Tran, 2025 11.10[0.06; 20.44]4749not evaluable Digestive system anomalies Tran, 2025 10.22[0.01; 3.62]22749not evaluable Duodenal atresia or stenosis Tran, 2025 19.90[0.20; 499.28]-749not evaluable Ear malformations Tran, 2025 19.90[0.20; 499.28]-749not evaluable Ebstein's anomaly Tran, 2025 19.90[0.20; 499.28]-749not evaluable Encephalocele Tran, 2025 19.90[0.20; 499.28]-749not evaluable Eye defects Tran, 2025 14.96[0.46; 53.36]-749not evaluable Genital anomalies Tran, 2025 11.38[0.66; 2.89]60749not evaluable Hypospadias Tran, 2025 11.18[0.42; 3.32]30749not evaluable Limb defects Tran, 2025 10.86[0.34; 2.18]63749not evaluable Major congenital malformations Tran, 2025 10.93[0.67; 1.29]4371,042not evaluable Microcephaly / Small head circumference for gestational age Tran, 2025 11.41[0.07; 27.39]3749not evaluable Nervous system anomalies Tran, 2025 10.47[0.03; 8.04]10749not evaluable Oesophageal atresia with or without tracheo-oesophageal fistula Tran, 2025 19.90[0.20; 499.28]-749not evaluable Oro-facial clefts Tran, 2025 10.40[0.02; 6.68]12749not evaluable Patent ductus arterious Tran, 2025 10.32[0.02; 5.33]15749not evaluable Polydactyly Tran, 2025 10.77[0.11; 5.49]4749not evaluable Posterior urethral valve and/or prune belly Tran, 2025 19.90[0.20; 499.28]-749not evaluable Respiratory system anomalies Tran, 2025 11.10[0.26; 4.66]9749not evaluable Single ventricle Tran, 2025 19.90[0.20; 499.28]-749not evaluable Transposition of the great vessels Tran, 2025 11.10[0.06; 20.44]4749not evaluable Urinary malformations Tran, 2025 11.27[0.53; 3.06]39749not evaluable Ventricular septal defect Tran, 2025 11.79[0.62; 5.16]26749not evaluable Growth parameters and prematurity Preterm (< 37 weeks) Bérard (Controls unexposed, sick), 2016 Tran (Controls unexposed, sick), 2020 20.31[0.06; 1.52]446304not evaluable Small for gestational age (weight) Bérard (Controls unexposed, sick), 2016 Tran (Controls unexposed, sick), 2020 20.91[0.65; 1.27]568304not evaluable Very preterm (28 to 32 weeks) Nanovskaya, 2017 11.16[0.07; 19.52]226not evaluable Maternal consequences Caesarean Tran (Controls unexposed, sick), 2020 11.15[0.78; 1.70]323232not evaluable Maternal consequences (as a whole) Tran (Controls unexposed, sick), 2020 10.95[0.37; 2.43]54232not evaluable Neonatal disorders Neonatal medical care Nanovskaya, 2017 Tran (Controls unexposed, sick), 2020 20.88[0.60; 1.27]361259not evaluable Neonatal disorders (as a whole) Tran (Controls unexposed, sick), 2020 10.87[0.50; 1.52]172232not evaluable Low Apgar score (< 7) (at 5 min) Kranzler, 2021 10.18[0.01; 3.91]261not evaluable0.0100.01.0

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