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Triazolam
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Noh, 2022
1
0.91
[
0.72
; 1.16]
156,966
1,299
not evaluable
Congenital heart defects
Noh, 2022
1
1.12
[
0.83
; 1.51]
83,629
1,299
not evaluable
Major congenital malformations
Noh, 2022
1
0.91
[
0.72
; 1.16]
156,966
1,299
not evaluable
Growth parameters and prematurity
Preterm (< 37 weeks)
Meng a (Controls unexposed, sick), 2023
1
1.37
[
1.10
; 1.71]
250,892
742
not evaluable
Small for gestational age (weight)
Meng a (Controls unexposed, sick), 2023
1
1.22
[
0.98
; 1.52]
266,254
749
not evaluable
Intrauterine deaths
Late intrauterine deaths (> 22 weeks) / Stillbirths
Meng a (Controls unexposed, sick), 2023
1
0.87
[
0.43
; 1.76]
32,331
750
not evaluable
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions
Sheehy, 2019
1
1.14
[
0.11
; 11.82]
27,149
5
not evaluable
0.0
20.0
1.0