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Flurazepam
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Noh, 2022
1
1.04
[
0.54
; 1.99]
156,905
159
not evaluable
Congenital heart defects
Noh, 2022
1
0.84
[
0.31
; 2.25]
83,588
159
not evaluable
Major congenital malformations
Noh, 2022
1
1.04
[
0.54
; 1.99]
156,905
159
not evaluable
Intrauterine deaths
Early intrauterine deaths (< 22 weeks) / Spontaneous abortions
Sheehy, 2019
1
1.13
[
0.36
; 3.57]
27,149
22
not evaluable
0.2
5.0
1.0
