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Clotiazepam
Overall results
Study description
Excluded studies
Table
Graphic
auto
during pregnancy (anytime or not specified)
1st trimester
2nd trimester
3rd trimester
2nd and/or 3rd trimester
throughout pregnancy
early pregnancy
days before delivery
late pregnancy
preconception-only
periconceptional
preconceptional for kinetic reason
at least 1st trimester
3 months (or more) before pregnancy or during pregnancy
1st and 2nd trimester
3 months or more before pregnancy or1st trimester
Whatever the period exposition
individual studies
Outcome
TE
95% CI
n cases
n exposed
k
Pub. bias
Congenital malformations
All congenital malformations (majors, minors, majors and minors, or unspecified)
Noh, 2022
1
0.91
[
0.75
; 1.11]
156,991
1,896
not evaluable
Congenital heart defects
Noh, 2022
1
0.90
[
0.69
; 1.18]
83,635
1,896
not evaluable
Major congenital malformations
Noh, 2022
1
0.91
[
0.75
; 1.11]
156,991
1,896
not evaluable
0.5
5.0
1.0