Phenobarbital (Epilepsy)


Study Exclusion reasons Rmk Reference
Coste (Phenobarbital) (Controls unexposed, sick), 2020 EXCLUDED: this control group doesn't exist in the article (only in the report). Children with a diagnosis of brain malformation (ICD-10 codes Q00 to Q04 and Q05.0 to Q05.4) during their stay in the maternity unit are excluded.

Coste Sci Rep 2020; 10:17362 10.1038/s41598-020-74409-x

Gopinath (Phenobarbital), 2015 repeat population groups, duplicate reports (most recent study included) Overlapping: Thomas 2022 included data on language and cognitive delay, also evaluated in Sreedharan et al., 2018; Thomas 2007 and Gopinath 2015, but with more exposed pregnancies, more relevant control group and older children => Use of Thomas 2022.

Gopinath Epilepsy Res 2015; 117:58-62 10.1016/j.eplepsyres.2015.09.003

Thomas (Phenobarbital), 2007 repeat population groups, duplicate reports (most recent study included) Overlapping: Thomas 2022 included data on language and cognitive delay, also evaluated in Sreedharan et al., 2018; Thomas 2007 and Gopinath 2015, but with more exposed pregnancies, more relevant control group and older children => Use of Thomas 2022.

Thomas Epilepsia 2007; 48:2234-40 10.1111/j.1528-1167.2007.01376.x