Opipramol - Medication and Pregnancy KB

Opipramol

Exposed non-exposed, cohort studies

Study	Country Study period Study design	Data source	Exposure definition	Non-exposure definition	Exposition period	Sample size (exposed/unexposed) Or (case / control)	Remarks	Risk of bias
Ozturk 2016	Turkey 2007 - 2012 prospective cohort	An observational cohort study based on a prenatal consultation service.	Pregnant women exposed to Opipramol during pregnancy. (This is a subgroup of exposure among the whole exposed group considered in the study).	unexposed (general population or NOS) Pregnant women selected from the non-teratogen exposed pregnancies in the same year.	at least 1st trimester	2 / 275	'Drug exposures took place in 81% during the first trimester, and 11% in all three trimesters. Medical treatments were discontinued in most of recognized pregnancies.'=> considered as 'At least first trimester'.
Ozturk 2016	Turkey 2007 - 2012 prospective cohort		At the first contact, initiated via gynecologists, a detailed patient history form was used to notably record all drug exposures (dose, duration and timing in pregnancy).		at least 1st trimester	2 / 275
Yaris 2005	Turkey 1999 - 2004 prospective cohort	Toxicology Information and Follow-up Service	Women who were exposed to Opipramol during pregnancy for depression, anxiety, and psychotic disorders. (This is a subgroup of exposure among the whole exposed group considered in the study).	unexposed (general population or NOS) Women who did not use any drug while pregnant.	during pregnancy (anytime or not specified)	8 / 248	Raw data for Intrauterine exitus not reported because the nb of cases in the unexposed group not clearly stated. Raw data for premature delivery not reported because the denominator is not clearly stated.
Yaris 2005	Turkey 1999 - 2004 prospective cohort	Toxicology Information and Follow-up Service	Data surveyed by the interviews.		during pregnancy (anytime or not specified)	8 / 248

Case-control studies

Study	Country Study period Study design	Data source	Case	Control	Exposition	Exposition period	Sample size (exposed/unexposed) Or (case / control)	Remarks	Risk of bias

Risk of bias: : NA; : low; : moderate; : serious; : critical; : unclear;

Empty. There are no case-control studies available for this drug.

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