Ondansetron

Atresia or stenosis of other parts of small intestine

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2746
R3940
Pasternak, 2013 Congenital absence, atresia and stenosis of small intestine, part unspecified 1st trimester population based cohort retrospective unexposed (general population or NOS) Adjustment: No 1.33 [0.05;32.76] C 0/1,233   1/4,932 1 1,233
ref
Total 1 studies 1.33 [0.05;32.76] 1 1,233
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Pasternak, 2013Pasternak, 2013 1.33[0.05; 32.76]11,2330%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.33[0.05; 32.76]11,233 -NAPasternak, 2013 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 1.33[0.05; 32.76]11,233 -NAPasternak, 2013 1 Tags Adjustment   - No  - No 1.33[0.05; 32.76]11,233 -NAPasternak, 2013 1 All studiesAll studies 1.33[0.05; 32.76]11,233 -NAPasternak, 2013 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 1.33[0.05; 32.76]11,233 -NAPasternak, 2013 1 unexposed, sick controlsunexposed, sick controls 0.96[0.61; 1.53]3936470%NAParker, BDS study, 2018 Parker, NBDPS study, 2018 20.510.01.0