Duloxetine updated on 07-01-2025

Ear malformations

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S11747
R43166
Huybrechts (Controls unexposed, NOS), 2020 Ear Anomalies 1st trimester retrospective cohort (claims database) unexposed (general population or NOS) excluded Adjustment: Yes Monotherapy: no or not specified 1.73 [0.24;12.39]
excluded (control group)
-/2,532   -/- - 2,532
ref
S11748
R43180
Huybrechts (Controls unexposed, sick), 2020 Ear Anomalies 1st trimester retrospective cohort (claims database) unexposed, sick Adjustment: Yes Monotherapy: no or not specified Unexposed sick: intermediate history of illness/treatment (3-12 months before pregnancy) no data -/2,532   -/2,456 - 2,532
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis