id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S9643 R34313 |
Veiby (Carbamazepine) (Controls exposed to Lamotrigine, sick) (Mixed indications), 2014 | Cardiac septal | throughout pregnancy | population based cohort retrospective | exposed to other treatment, sick excluded | Adjustment: No |
0.76 [0.25;2.33] C excluded (control group) |
5/685 8/833 | 13 | 685 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9645 R34323 |
Veiby (Carbamazepine) (Controls unexposed, disease free) (Mixed indications), 2014 | Cardiac septal | throughout pregnancy | population based cohort retrospective | unexposed, disease free | Adjustment: No | 1.04 [0.43;2.52] C | 5/685 5,400/771,412 | 5,405 | 685 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9625 R34226 |
Källén (Carbamazepine) (Controls exposed to Lamotrigine, sick) (Indications NOS), 2013 | Septum defect | early pregnancy | population based cohort retrospective | exposed to other treatment, sick excluded | Adjustment: No |
0.56 [0.25;1.24] C excluded (control group) |
11/1,511 14/1,084 | 25 | 1,511 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9626 R34234 |
Källén (Carbamazepine) (Controls unexposed, NOS) (Indications NOS), 2013 | Septum defect | early pregnancy | population based cohort retrospective | unexposed (general population or NOS) | Adjustment: Yes | 0.81 [0.48;1.55] | 11/1,511 11,155/1,575,847 | 11,166 | 1,511 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 0.88 [0.54;1.43] | 16,571 | 2,196 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Carbamazepine) (Controls unexposed, disease free) (Mixed indications; 2: Carbamazepine) (Controls unexposed, NOS) (Indications NOS;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 9625, 9643