Carbamazepine (All indications)

Maternal consequences (as a whole)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S12702
R47938		 Alsfouk (Carbamazepine), 2022 Maternal complication (bleeding during pregnancy, gestational hypertension, eclampsia, preeclampsia, gestational diabetes, cervical cerclage, placenta abruption, prolonged labor, pre-mature rupture of membranes, seizure on day of delivery or during delivery, and post-partum hemorrhage) during pregnancy (anytime or not specified) retrospective cohort exposed to other treatment, sick Adjustment: No 2.53 [0.59;10.85] C 12/31   3/15 15 31
ref
Total 1 studies 2.53 [0.59;10.85] 15 31
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Alsfouk (Carbamazepine), 2022Alsfouk, 2022 1 2.53[0.59; 10.85]15310%ROB confusion: criticalROB selection: criticalROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Carbamazepine;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.53[0.59; 10.85]1531 -NAAlsfouk (Carbamazepine), 2022 1 case control studiescase control studies 0 Type of controls exposed to other treatment, sickexposed to other treatment, sick 2.53[0.59; 10.85]1531 -NAAlsfouk (Carbamazepine), 2022 1 Tags Adjustment   - No  - No 2.53[0.59; 10.85]1531 -NAAlsfouk (Carbamazepine), 2022 1 All studiesAll studies 2.53[0.59; 10.85]1531 -NAAlsfouk (Carbamazepine), 2022 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls exposed to other treatment, sick controlsexposed to other treatment, sick controls 2.53[0.59; 10.85]1531 -NAAlsfouk (Carbamazepine), 2022 10.510.01.0