id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S9160 R31485 |
Coste (Phenobarbital) (Controls exposed to Lamotrigine, sick), 2020 | Weight at birth (≥3500 g) | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | exposed to other treatment, sick excluded | Adjustment: No Controls: mixed indications |
0.56 [0.33;0.96] C excluded (control group) |
17/84 879/2,813 | 896 | 84 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9161 R31503 |
Coste (Phenobarbital) (Controls unexposed, NOS), 2020 | Weight at birth (≥3500 g) | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | unexposed (general population or NOS) | Adjustment: No | 0.50 [0.29;0.85] C | 17/84 577,097/1,710,441 | 577,114 | 84 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9105 R31279 |
Endo (Phenobarbital) (Controls unexposed, sick), 2004 | Birth weight > 4,000g | throughout pregnancy | retrospective cohort | unexposed, sick | Adjustment: No | 0.05 [0.00;6.68] C | 0/10 0/1 | 0 | 10 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 0.49 [0.29;0.82] | 577,114 | 94 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Phenobarbital) (Controls unexposed, NOS; 2: Phenobarbital) (Controls unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 9160