id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S9042 R30867 |
Bank (Oxcarbazepine) (Mixed indications), 2017 | Apgar < 7 at 1 minute | during pregnancy (anytime or not specified) | prospective cohort | exposed to other treatment, sick | Adjustment: No | 1.91 [0.08;48.39] C | 0/4 2/36 | 2 | 4 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9036 R30804 |
Artama (Oxcarbazepine) (Controls exposed to Lamotrigine, sick), 2013 | 1-min Apgar <7 | 3rd trimester | population based cohort retrospective | exposed to other treatment, sick excluded | Adjustment: No |
0.99 [0.46;2.16] C excluded (control group) |
27/465 9/154 | 36 | 465 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9037 R30816 |
Artama (Oxcarbazepine) (Controls unexposed, disease free), 2013 | 1-min Apgar <7 | 3rd trimester | population based cohort retrospective | unexposed, disease free excluded | Adjustment: Yes |
1.33 [0.90;1.97] excluded (control group) |
27/465 27,939/689,482 | 27,966 | 465 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9038 R30828 |
Artama (Oxcarbazepine) (Controls unexposed, sick), 2013 | 1-min Apgar <7 | 3rd trimester | population based cohort retrospective | unexposed, sick | Adjustment: Yes | 1.33 [0.83;2.12] | 27/465 69/1,708 | 96 | 465 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 1.34 [0.84;2.13] | 98 | 469 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Oxcarbazepine) (Mixed indications; 2: Oxcarbazepine) (Controls unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 9036, 9037