id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S12825 R48280 |
Thomas (Levetiracetam) (Controls exposed to Lamotrigine, sick), 2021 | Urinary malformations | 1st trimester | prospective cohort | exposed to other treatment, sick excluded | Adjustment: No |
0.47 [0.03;7.62] C excluded (control group) |
1/106 1/50 | 2 | 106 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S12827 R48292 |
Thomas (Levetiracetam) (Controls unexposed, sick), 2021 | Urinary malformations | 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 0.53 [0.06;4.45] C | 1/106 6/340 | 7 | 106 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9010 R30653 |
Tomson (Levetiracetam), 2018 | Renal malformations | at least 1st trimester | prospective cohort | exposed to other treatment, sick | Adjustment: No | 0.52 [0.07;4.20] C | 1/599 8/2,514 | 9 | 599 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 0.53 [0.12;2.33] | 16 | 705 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Levetiracetam) (Controls unexposed, sick; 2: Levetiracetam;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 12825