id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S15218 R62394 |
Bromley (Lamotrigine) (Epilepsy), 2023 | Neonatal complications | during pregnancy (anytime or not specified) | prospective cohort | unexposed, sick | Adjustment: No | 1.20 [0.58;2.48] C | 23/106 15/80 | 38 | 106 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8978 R30435 |
Coste (Lamotrigine) (Controls unexposed NOS) (Mixed indications), 2020 | Neonatal condition | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | unexposed (general population or NOS) | Adjustment: No | 0.95 [0.85;1.06] C | 349/2,813 221,770/1,707,707 | 222,119 | 2,813 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 0.95 [0.85;1.07] | 222,157 | 2,919 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Lamotrigine) (Epilepsy; 2: Lamotrigine) (Controls unexposed NOS) (Mixed indications;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded