id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S12611 R47527 |
Van Marter (Lamotrigine) (Controls unexposed, disease free), 2021 | Prematurity - Moderate (28-33 wk gestational age) | at least 1st trimester | prospective cohort | unexposed, disease free excluded | Adjustment: No |
0.96 [0.06;15.60] C excluded (control group) |
1/110 1/106 | 2 | 110 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S12613 R47539 |
Van Marter (Lamotrigine) (Controls unexposed, sick), 2021 | Prematurity - Moderate (28-33 wk gestational age) | at least 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 0.13 [0.01;2.17] C | 1/110 1/15 | 2 | 110 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8978 R30428 |
Coste (Lamotrigine) (Controls unexposed NOS) (Mixed indications), 2020 | Gestational age at birth (27–31 WA) | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | unexposed (general population or NOS) | Adjustment: No | 0.64 [0.33;1.23] C | 9/2,813 8,556/1,707,707 | 8,565 | 2,813 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 0.53 [0.19;1.45] | 8,567 | 2,923 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Lamotrigine) (Controls unexposed, sick; 2: Lamotrigine) (Controls unexposed NOS) (Mixed indications;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 12611