id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S8964 R30358 |
Veiby (Lamotrigine) (Controls unexposed, disease free) (Mixed indications), 2014 | Cardiac septal | throughout pregnancy | population based cohort retrospective | unexposed, disease free | Adjustment: No | 1.38 [0.69;2.76] C | 8/833 5,400/771,412 | 5,408 | 833 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8908 R30104 |
Källén (Lamotrigine) (Indications NOS), 2013 | Septum defect | early pregnancy | population based cohort retrospective | unexposed (general population or NOS) | Adjustment: Yes | 1.52 [0.83;2.55] | 14/1,084 11,155/1,575,847 | 11,169 | 1,084 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 1.46 [0.94;2.26] | 16,577 | 1,917 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Lamotrigine) (Controls unexposed, disease free) (Mixed indications; 2: Lamotrigine) (Indications NOS;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded