id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S8902 R30059 |
Artama (Lamotrigine) (Controls unexposed, disease free), 2013 | Caesarean section | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed, disease free excluded | Adjustment: Yes |
1.20 [0.81;1.77] excluded (control group) |
32/173 114,791/721,948 | 114,823 | 173 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8903 R30071 |
Artama (Lamotrigine) (Controls unexposed, sick), 2013 | Caesarean section | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed, sick | Adjustment: Yes | 0.93 [0.61;1.42] | 32/173 331/1,800 | 363 | 173 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8952 R30266 |
Rihtman (Lamotrigine), 2013 | Cesarean section | at least 1st trimester excluded | prospective cohort | unexposed (general population or NOS) | Adjustment: No |
2.07 [0.54;7.92] C excluded (exposition period) |
6/40 4/51 | 10 | 40 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8957 R30333 |
Borthen (Lamotrigine) (Controls unexposed, disease free), 2010 | Caesarean | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed, disease free excluded | Adjustment: Yes |
1.40 [1.00;1.90] excluded (control group) |
44/233 51,806/362,302 | 51,850 | 233 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S8959 R30341 |
Borthen (Lamotrigine) (Controls unexposed, sick), 2010 | Caesarean | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed, sick | Adjustment: No | 1.05 [0.74;1.49] C | 44/233 337/1,863 | 381 | 233 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 1.00 [0.77;1.31] | 744 | 406 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Lamotrigine) (Controls unexposed, sick; 2: Lamotrigine) (Controls unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 8957, 8902