Gabapentin (All indications)

Neonatal medical care

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S15270
R62759		 Desrochers, 2022 Neonatal intensive care unit admissions during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed (general population or NOS) Adjustment: Yes 2.18 [1.81;2.62] -/870   -/288,357 - 870
ref
Total 1 studies 2.18 [1.81;2.62] 0 870
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Desrochers, 2022Desrochers, 2022 2.18[1.81; 2.62]-8700%ROB confusion: unclearROB selection: unclearROB classification: unclearROB missing: unclearROB mesure: unclearROB reporting: moderate0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.18[1.81; 2.62]-870 -NADesrochers, 2022 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 2.18[1.81; 2.62]-870 -NADesrochers, 2022 1 Tags Adjustment   - Yes  - Yes 2.18[1.81; 2.62]-870 -NADesrochers, 2022 1 All studiesAll studies 2.18[1.81; 2.62]-870 -NADesrochers, 2022 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 2.18[1.81; 2.62]-870 -NADesrochers, 2022 10.510.01.0