id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S6681 R18530 |
Dean (Primidone), 2002 | Minor congenital malformations | at least 1st trimester | retrospective cohort | unexposed, sick | Adjustment: No | 1.97 [0.07;54.80] C | 0/2 5/38 | 5 | 2 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S7274 R21043 |
Battino (Primidone), 1992 | Minor anomalies | 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 5.43 [0.28;105.58] C | 7/31 0/9 | 7 | 31 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 3.46 [0.38;31.70] | 12 | 33 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Primidone; 2: Primidone;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded