id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S7417 R21837 |
Miškov (Phenobarbital) (Controls exposed to Lamotrigine, sick), 2016 | Spontaneous abortion | during pregnancy (anytime or not specified) | prospective cohort | exposed to other treatment, sick excluded | Adjustment: No |
5.67 [0.39;82.24] C excluded (control group) |
1/3 3/37 | 4 | 3 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S7047 R19898 |
Miškov (Phenobarbital) (Controls unexposed, disease free), 2016 | Spontaneous abortion | during pregnancy (anytime or not specified) | prospective cohort | unexposed, disease free excluded | Adjustment: No |
255.00 [7.09;9172.13] C excluded (control group) |
1/3 0/128 | 1 | 3 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S7412 R21815 |
Miškov (Phenobarbital) (Controls unexposed, sick), 2016 | Spontaneous abortion | during pregnancy (anytime or not specified) | prospective cohort | unexposed, sick | Adjustment: No | 7.00 [0.17;291.36] C | 1/3 0/4 | 1 | 3 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S7817 R23217 |
Tomson (Phenobarbital), 2015 | Spontaneous abortions | at least 1st trimester | prospective cohort | exposed to other treatment, sick | Adjustment: No | 1.02 [0.63;1.66] C | 20/260 144/1,910 | 164 | 260 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 1.06 [0.63;1.79] | 165 | 263 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Phenobarbital) (Controls unexposed, sick; 2: Phenobarbital;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 7417, 7047