id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S7514 R47136 |
Thomas (Controls unexposed, sick), 2021 | Skeletal malformations | 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 1.36 [0.06;28.82] C | 0/50 2/340 | 2 | 50 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9826 R37686 |
Vajda, 2013 | Skeletal / Limb Malformations | at least 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 0.15 [0.01;3.81] C | 0/315 1/147 | 1 | 315 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9843 R35299 |
Mawer (Controls unexposed, disease free), 2010 | Skeletal / Limb Malformations | 1st trimester | prospective cohort | unexposed, disease free excluded | Adjustment: No Matched |
24.04 [0.96;601.51] C excluded (control group) |
1/37 0/285 | 1 | 37 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9844 R35305 |
Mawer (Controls unexposed, sick), 2010 | Skeletal / Limb Malformations | 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 3.42 [0.14;86.71] C | 1/37 0/41 | 1 | 37 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 3 studies | 0.90 [0.15;5.60] | 4 | 402 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Controls unexposed, sick; 2: Controls unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 9843