id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S7514 R47133 |
Thomas (Controls unexposed, sick), 2021 | Cardiac malformations | 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 0.75 [0.09;6.05] C | 1/50 9/340 | 10 | 50 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S7719 R35919 |
Diav-Citrin, 2017 | Cardiovascular anomalies without chromosomal anomalies | at least 1st trimester | prospective cohort | unexposed, disease free | Adjustment: No | 2.46 [0.66;9.22] C | 3/114 9/828 | 12 | 114 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9826 R37684 |
Vajda, 2013 | Cardiac Malformations | at least 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 1.40 [0.14;13.61] C | 3/315 1/147 | 4 | 315 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9843 R35297 |
Mawer (Controls unexposed, disease free), 2010 | Cardiac Malformations | 1st trimester | prospective cohort | unexposed, disease free excluded | Adjustment: No Matched |
2.59 [0.10;64.75] C excluded (control group) |
0/37 1/285 | 1 | 37 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S9844 R35303 |
Mawer (Controls unexposed, sick), 2010 | Cardiac Malformations | 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 1.11 [0.02;57.36] C | 0/37 0/41 | 0 | 37 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 4 studies | 1.64 [0.62;4.32] | 26 | 516 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Controls unexposed, sick; 2: Controls unexposed, sick;
Asymetry test p-value = NaN (by Egger's regression)
not enought points
excluded 9843