Antimycotic Azoles (all routes except local only) updated on 01-29-2025

Caesarean

id	Study   Auto Bar-Oz - Itraconazole, 2000Mastroiacovo - Fluconazole, 1996	Lib. in paper	Exposition period  Auto during pregnancy (anytime or not specified)1st trimester2nd trimester3rd trimester2nd and/or 3rd trimesterthroughout pregnancyearly pregnancydays before deliverylate pregnancypreconception-onlypericonceptionalpreconceptional for kinetic reasonat least 1st trimester3 months (or more) before pregnancy or during pregnancy1st and 2nd trimester3 months or more before pregnancy or1st trimester	Study type  All studies Case control excluded Only case control	Control type    Auto unexposed (general population or NOS)unexposed, sickunexposed, disease freeexposed to other treatment, sicknot specifiedsiblingwhatever (meta-analysis)	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S17747 R75055	Bar-Oz - Itraconazole, 2000	Cesarean	1st trimester excluded	prospective cohort	unexposed (general population or NOS)	Adjustment: No Matched	1.47 [1.04;2.09] excluded (exposition period)	23/99   26/188	49	99		ref
S17733 R74846	Mastroiacovo - Fluconazole, 1996	Cesarean section	1st trimester excluded	prospective cohort	unexposed (general population or NOS)	Adjustment: Yes Fluconazole not specified or mixed dose Matched	0.91 [0.60;1.40] excluded (exposition period)	-/169   -/389	-	169		ref
					Total	0 studies	NaN [NaN;NaN]		0	0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis