Sertraline updated on 07-01-2025

Elective/induced termination of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S7522
R22549		 Ozturk (Sertraline), 2016 Elective termination of pregnancy at least 1st trimester prospective cohort unexposed (general population or NOS) Adjustment: No Monotherapy: no or not specified 2.19 [0.46;10.45] C 2/19   14/275 16 19
ref
Total 1 studies 2.19 [0.46;10.45] 16 19
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Ozturk (Sertraline), 2016Ozturk, 2016 1 2.19[0.46; 10.45]16190%ROB confusion: criticalROB selection: unclearROB classification: moderateROB missing: lowROB mesure: moderateROB reporting: moderate0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Sertraline;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.19[0.46; 10.45]1619 -NAOzturk (Sertraline), 2016 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 2.19[0.46; 10.45]1619 -NAOzturk (Sertraline), 2016 1 Tags Adjustment   - No  - No 2.19[0.46; 10.45]1619 -NAOzturk (Sertraline), 2016 1 Monotherapy   - no or not specified  - no or not specified 2.19[0.46; 10.45]1619 -NAOzturk (Sertraline), 2016 1 All studiesAll studies 2.19[0.46; 10.45]1619 -NAOzturk (Sertraline), 2016 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 2.19[0.46; 10.45]1619 -NAOzturk (Sertraline), 2016 10.510.01.0