Econazole updated on 01-29-2025

Bilateral renal agenesis including Potter syndrome

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S17546
R73877		 Czeizel, 2003 Renal agenesis 1st trimester case control unexposed (general population or NOS) Adjustment: No Matched Route of exposure Azoles: Vaginal 9.45 [0.57;157.50] C 0/19   104/38,236 104 19
ref
Total 1 studies 9.45 [0.57;157.50] 104 19
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Czeizel, 2003Czeizel, 2003 9.45[0.57; 157.50]104190%ROB confusion: unclearROB selection: criticalROB classification: moderateROB missing: moderateROB mesure: criticalROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 9.45[0.57; 157.50]10419 -NACzeizel, 2003 1 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 9.45[0.57; 157.50]10419 -NACzeizel, 2003 1 Tags Adjustment   - No  - No 9.45[0.57; 157.50]10419 -NACzeizel, 2003 1 MatchedMatched 9.45[0.57; 157.50]10419 -NACzeizel, 2003 1 Route of exposure Azoles   - Vaginal  - Vaginal 9.45[0.57; 157.50]10419 -NACzeizel, 2003 1 All studiesAll studies 9.45[0.57; 157.50]10419 -NACzeizel, 2003 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 9.45[0.57; 157.50]10419 -NACzeizel, 2003 10.510.01.0