Metronidazole (all routes except local only) updated on 01-29-2025

Neonatal antibiotic resistance

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S17605
R74308		 Wright, 2012 Antibiotic resistance in early-onset neonatal sepsis (EOS) during pregnancy (anytime or not specified) case control exposed to other treatment, sick Adjustment: No 4.66 [0.21;101.47] C 2/2   30/58 32 2
ref
Total 1 studies 4.66 [0.21;101.47] 32 2
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Wright, 2012Wright, 2012 4.66[0.21; 101.47]3220%ROB confusion: criticalROB selection: criticalROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 4.66[0.21; 101.47]322 -NAWright, 2012 1 Type of controls exposed to other treatment, sickexposed to other treatment, sick 4.66[0.21; 101.47]322 -NAWright, 2012 1 Tags Adjustment   - No  - No 4.66[0.21; 101.47]322 -NAWright, 2012 1 All studiesAll studies 4.66[0.21; 101.47]322 -NAWright, 2012 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls exposed to other treatment, sick controlsexposed to other treatment, sick controls 4.66[0.21; 101.47]322 -NAWright, 2012 10.510.01.0