Frovatriptan

Major congenital malformations

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3525
R6970
Spielmann (Control mainly exposed other treatments, sick), 2017 Major birth defects during pregnancy (anytime or not specified) prospective cohort exposed to other treatment, sick excluded Adjustment: No 1.93 [0.24;15.67] C
excluded (control group)
1/19   12/429 13 19
ref
S3526
R6971
Spielmann (Control unexposed, disease free), 2017 Major birth defects during pregnancy (anytime or not specified) excluded prospective cohort unexposed, disease free Adjustment: No 1.87 [0.24;14.33] C
excluded (exposition period)
1/19   44/1,526 45 19
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis