TNF-alpha inhibitors

Eye defects

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S4098
R8750
Carman - Etanercept (Controls unexposed, disease free), 2017 Eye malformations during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed, disease free excluded Adjustment: No 0.73 [0.04;14.24] C
excluded (control group)
0/210   3/1,078 3 210
ref
S4099
R8765
Carman - Etanercept (Controls unexposed, sick), 2017 Eye malformations during pregnancy (anytime or not specified) excluded retrospective cohort (claims database) unexposed, sick Adjustment: No 3.07 [0.12;75.64] C
excluded (exposition period)
0/210   1/1,932 1 210
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis